Oligonucleotides Designed to Inhibit TLR9 Block Herpes Simplex Virus type 1 Infection at Multiple Steps

Herpes simplex virus type 1 (HSV-1) is an important human pathogen which requires activation of nuclear factor–kappa B (NFκB) during its replication cycle. The persistent nature of HSV-1 infection, and the emergence of drug-resistant strains, highlights the importance of research to develop new anti...

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Bibliographic Details
Main Authors: Sauter, Monica M., Gauger, Joshua J. L., Brandt, Curtis R.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135040/
https://ncbi.nlm.nih.gov/pubmed/24995383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.06.015
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