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Dichotomous Effects of IFNγ on Dendritic Cell Function Determine the Extent of Interleukin-12-driven Antitumor T-cell Immunity
Sustained intratumoral delivery of Interleukin-12 (IL-12) and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) can overcome tumor immune suppression and promote T-cell-dependent eradication of established disease in murine tumor models. However the antitumor effector response is transient a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119751/ https://ncbi.nlm.nih.gov/pubmed/21632715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100168 |
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