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Central Role of IFNγ-Indoleamine 2,3 Dioxygenase Axis in Regulation of Interleukin-12-mediated Antitumor Immunity
Sustained intratumoral delivery of IL-12 and GM-CSF induces tumor regression via restoration of tumor-resident CD8+ T-effector/memory cell cytotoxicity and subsequent re-priming of a secondary CD8+ T-effector cell response in tumor-draining lymph nodes (TDLN). However, treatment-induced T-effector a...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805056/ https://ncbi.nlm.nih.gov/pubmed/20028855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3170 |
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