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EGF receptor kinase activity is required for gap junction closure and for part of the decrease in ovarian follicle cGMP in response to luteinizing hormone.

The meiotic cell cycle in mouse oocytes is arrested in prophase, and then restarted when luteinizing hormone (LH) acts on the surrounding granulosa cells. The granulosa cells keep meiosis arrested by providing a source of cGMP that diffuses into the oocyte through gap junctions, and LH restarts the...

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Hlavní autoři: Norris, Rachael P, Freudzon, Marina, Nikolaev, Viacheslav O, Jaffe, Laurinda A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119707/
https://ncbi.nlm.nih.gov/pubmed/20826538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-10-0288
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