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Chimeric Antigen Receptor Therapy for B-cell Malignancies

We presented data showing that the CART-19 cells expressing the 4-1BB signaling domain can have unprecedented and massive in-vivo expansion, traffic to tumor sites, persist long term in vivo, and induce rapid and potent anti-tumor activity in chemotherapy refractory CLL patients.

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Detalhes bibliográficos
Main Authors: Porter, David L, Kalos, Michael, Zheng, Zhaohui, Levine, Bruce, June, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119397/
https://ncbi.nlm.nih.gov/pubmed/21716851
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