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Thiazolidinediones inhibit MDCK cyst growth through disrupting oriented cell division and apicobasal polarity
Thiazolidinediones have been reported to retard cystic disease in rodent models by uncertain mechanisms. We hypothesized that their major effect in retarding cystogenesis was through inhibiting cell proliferation or stimulating apoptosis. In the Madin-Darby canine kidney cell (MDCK) model, rosiglita...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119142/ https://ncbi.nlm.nih.gov/pubmed/21429973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00482.2010 |
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