TTC7A mutations disrupt intestinal epithelial apicobasal polarity

Multiple intestinal atresia (MIA) is a rare cause of bowel obstruction that is sometimes associated with a combined immunodeficiency (CID), leading to increased susceptibility to infections. The factors underlying this rare disease are poorly understood. We characterized the immunological and intest...

Full description

Saved in:
Bibliographic Details
Main Authors: Bigorgne, Amélie E., Farin, Henner F., Lemoine, Roxane, Mahlaoui, Nizar, Lambert, Nathalie, Gil, Marine, Schulz, Ansgar, Philippet, Pierre, Schlesser, Patrick, Abrahamsen, Tore G., Oymar, Knut, Davies, E. Graham, Ellingsen, Christian Lycke, Leteurtre, Emmanuelle, Moreau-Massart, Brigitte, Berrebi, Dominique, Bole-Feysot, Christine, Nischke, Patrick, Brousse, Nicole, Fischer, Alain, Clevers, Hans, de Saint Basile, Geneviève
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871247/
https://ncbi.nlm.nih.gov/pubmed/24292712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71471
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items