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Thiazolidinediones inhibit MDCK cyst growth through disrupting oriented cell division and apicobasal polarity

Thiazolidinediones have been reported to retard cystic disease in rodent models by uncertain mechanisms. We hypothesized that their major effect in retarding cystogenesis was through inhibiting cell proliferation or stimulating apoptosis. In the Madin-Darby canine kidney cell (MDCK) model, rosiglita...

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Detalhes bibliográficos
Main Authors: Mao, Zhiguo, Streets, Andrew J., Ong, Albert C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119142/
https://ncbi.nlm.nih.gov/pubmed/21429973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00482.2010
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