Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury

AMPK activation during ischemia helps the myocardium to cope with the deficit of energy production. As AMPK activity is considered to be impaired in diabetes, we hypothesized that enhancing AMPK activation during ischemia above physiological levels would protect the ischemic diabetic heart through A...

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Autors principals: Paiva, Marta A., Rutter-Locher, Zoe, Gonçalves, Lino M., Providência, Luís A., Davidson, Sean M., Yellon, Derek M., Mocanu, Mihaela M.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
Matèries:
Energetics and Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119096/
https://ncbi.nlm.nih.gov/pubmed/21421816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00707.2010
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