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Dynamic molecular and histopathological changes in the extracellular matrix and inflammation in the transition to heart failure in isolated volume overload

Left ventricular (LV) volume overload (VO) causes eccentric remodeling with inflammatory cell infiltration and extracellular matrix (ECM) degradation, for which there is currently no proven therapy. To uncover new pathways that connect inflammation and ECM homeostasis with cellular dysfunction, we d...

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Detalhes bibliográficos
Main Authors: Chen, Yuan-wen, Pat, Betty, Gladden, James D., Zheng, Junying, Powell, Pamela, Wei, Chih-Chang, Cui, Xiangqin, Husain, Ahsan, Dell'Italia, Louis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119090/
https://ncbi.nlm.nih.gov/pubmed/21421827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01104.2010
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