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Exome Sequencing Reveals Comprehensive Genomic Alterations across Eight Cancer Cell Lines

It is well established that genomic alterations play an essential role in oncogenesis, disease progression, and response of tumors to therapeutic intervention. The advances of next-generation sequencing technologies (NGS) provide unprecedented capabilities to scan genomes for changes such as mutatio...

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Detalhes bibliográficos
Main Authors: Chang, Han, Jackson, Donald G., Kayne, Paul S., Ross-Macdonald, Petra B., Ryseck, Rolf-Peter, Siemers, Nathan O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118809/
https://ncbi.nlm.nih.gov/pubmed/21701589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021097
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