Whole exome sequencing reveals minimal differences between cell line and whole blood derived DNA

Two common sources of DNA for whole exome sequencing (WES) are whole blood (WB) and immortalized lymphoblastoid cell line (LCL). However, it is possible that LCLs have a substantially higher rate of mutation than WB, causing concern for their use in sequencing studies. We compared results from paire...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schafer, Chad M., Campbell, Nicholas G., Cai, Guiqing, Yu, Fei, Makarov, Vladimir, Yoon, Seungtai, Daly, Mark J., Gibbs, Richard A., Schellenberg, Gerard D., Devlin, Bernie, Sutcliffe, James S., Buxbaum, Joseph D., Roeder, Kathryn
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812417/
https://ncbi.nlm.nih.gov/pubmed/23743231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2013.05.005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados