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Second generation sequencing allows for mtDNA mixture deconvolution and high resolution detection of heteroplasmy
AIM: To use parallel array pyrosequencing to deconvolute mixtures of mitochondrial DNA (mtDNA) sequence and provide high resolution analysis of mtDNA heteroplasmy. METHODS: The hypervariable segment 1 (HV1) of the mtDNA control region was analyzed from 30 individuals using the 454 GS Junior instrume...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Croatian Medical Schools
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118725/ https://ncbi.nlm.nih.gov/pubmed/21674826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3325/cmj.2011.52.299 |
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