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Hypertrophic cardiomyopathy: from mutation to functional analysis of defective protein

AIM: To analyze the genesis of hypertrophic cardiomyopathy on a large cohort of patients from molecular genetics point of view and perform the functional analysis of the 3D molecular model of defective myosin-7 protein in silico. METHODS: The study enrolled 153 patients with diagnosed hypertrophic c...

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Autori principali: Capek, Pavel, Vondrasek, Jiri, Skvor, Jiri, Brdicka, Radim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Croatian Medical Schools 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118724/
https://ncbi.nlm.nih.gov/pubmed/21674835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3325/cmj.2011.52.384
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