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DNA amplification--deletion in a spontaneous mutation of the hamster aprt locus: structure and sequence of the novel joint.

In a collection of spontaneous mutants of Chinese hamster ovary cells selected for deficiency in adenine phosphoribosyl transferase (aprt) activity, one was detected having not only a deletion of aprt coding sequences but also an apparent amplification of remaining sequences. The HindIII fragment be...

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Détails bibliographiques
Auteurs principaux: Nalbantoglu, J, Meuth, M
Format: Artigo
Langue:Inglês
Publié: 1986
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC311864/
https://ncbi.nlm.nih.gov/pubmed/3024103
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