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DNA amplification--deletion in a spontaneous mutation of the hamster aprt locus: structure and sequence of the novel joint.

In a collection of spontaneous mutants of Chinese hamster ovary cells selected for deficiency in adenine phosphoribosyl transferase (aprt) activity, one was detected having not only a deletion of aprt coding sequences but also an apparent amplification of remaining sequences. The HindIII fragment be...

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Publicat a:Nucleic Acids Res
Autors principals: Nalbantoglu, J, Meuth, M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1986
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311864/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3024103/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.21.8361
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