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Dual-Functional, Receptor-Targeted Fluorogenic Probe for In Vivo Imaging of Extracellular Protease Expressions
Herein we report a new type of in vivo fluorogenic probe that enables simultaneous and active targeting of overexpressed receptors, α(v)β(3) integrins, and extracellular proteases, matrix metalloproteinases (MMPs), in the tumor regions. This c(RGDyK)-conjugated MMP fluorogenic probe efficiently targ...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118575/ https://ncbi.nlm.nih.gov/pubmed/21574650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200005w |
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