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A self-immobilizing near-infrared fluorogenic probe for sensitive imaging of extracellular enzyme activity in vivo

Reported herein is a self-immobilizing near-infrared fluorogenic probe that can be used to image extracellular enzyme activity in vivo. Using a fluorophore as a quinone methide precursor, this probe covalently anchors at sites of activation and greatly enhances the fluorescence intensity at 710 nm u...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Li, Yuyao, Song, Heng, Xue, Chenghong, Fang, Zhijun, Xiong, Liqin, Xie, Hexin
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449546/
https://ncbi.nlm.nih.gov/pubmed/32874510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc01273d
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