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Immunosuppression alters disease severity in juvenile Batten disease mice
Autoantibodies to brain proteins are present in Juvenile Neuronal Ceroid Lipofuscinosis (Batten disease) patients and the Cln3(−/−) mouse model of this disease, suggesting an autoimmune component to pathogenesis. Using genetic or pharmaceutical approaches to attenuate this immune response in Cln3(−/...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118572/ https://ncbi.nlm.nih.gov/pubmed/20937531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.08.024 |
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