A carregar...
The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models
As key molecules which drive progression and chemoresistance in gastrointestinal cancers, EGFR and HER2 have become efficacious drug targets in this setting. Lapatinib is an EGFR/HER2 kinase inhibitor suppressing signaling through the RAS/RAF/MEK/MAPK and PI3K/AKT pathways. Histone deacetylase inhib...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118510/ https://ncbi.nlm.nih.gov/pubmed/21464044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2430 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|