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DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines

BACKGROUND: Despite the significant progress made in colon cancer chemotherapy, advanced disease remains largely incurable and novel efficacious chemotherapies are urgently needed. Histone deacetylase inhibitors (HDACi) represent a novel class of agents which have demonstrated promising preclinical...

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Main Authors: LaBonte, Melissa J, Wilson, Peter M, Fazzone, William, Groshen, Susan, Lenz, Heinz-Josef, Ladner, Robert D
格式: Artigo
語言:Inglês
出版: BioMed Central 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799439/
https://ncbi.nlm.nih.gov/pubmed/19948057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-67
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