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Functional analysis of the murine IgH enhancer: evidence for negative control of cell-type specificity.

We have carried out a mutational analysis of the mouse IgH enhancer. Consistent with previous reports, deletions extending from either the 5' side or the 3' side of the enhancer fail to reveal distinct boundaries which define enhancer function in lymphoid cells. Interestingly, internal point mutatio...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Kadesch, T, Zervos, P, Ruezinsky, D
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1986
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311845/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3095795/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.20.8209
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