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Identification of Genes Regulating Gene Targeting by a High-Throughput Screening Approach

Homologous gene targeting (HGT) is a precise but inefficient process for genome engineering. Several methods for increasing its efficiency have been developed, including the use of rare cutting endonucleases. However, there is still room for improvement, as even nuclease-induced HGT may vary in effi...

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Détails bibliographiques
Auteurs principaux: Delacôte, Fabien, Perez, Christophe, Guyot, Valérie, Mikonio, Catherine, Potrel, Pierrick, Cabaniols, Jean-Pierre, Delenda, Christophe, Pâques, Frédéric, Duchateau, Philippe
Format: Artigo
Langue:Inglês
Publié: SAGE-Hindawi Access to Research 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118287/
https://ncbi.nlm.nih.gov/pubmed/21716659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/947212
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