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Tec family kinases Itk and Rlk/Txk in T lymphocytes: Cross-regulation of cytokine production and T cell fates

Developing thymocytes and T cells express the Tec kinases Itk, Rlk/Txk and Tec, which are critical modulators of T cell receptor signaling, required for full activation of phospholipase C-γ and downstream Ca(2+) and ERK-mediated signaling pathways. Over the last 10 years, data have implicated the Te...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gomez-Rodriguez, Julio, Kraus, Zachary J., Schwartzberg, Pamela L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117960/
https://ncbi.nlm.nih.gov/pubmed/21362139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2011.08072.x
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