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Efficacy Study of Novel Diamidine Compounds in a Trypanosoma evansi Goat Model
Three diamidines (DB 75, DB 867 and DB 1192) were selected and their ability to cure T. evansi experimentally infected goats was investigated. A toxicity assessment and pharmacokinetic analysis of these compounds were additionally carried out. Goats demonstrated no signs of acute toxicity, when trea...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117839/ https://ncbi.nlm.nih.gov/pubmed/21698106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020836 |
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