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The Loss of the p53 Activator HIPK2 Is Responsible for Galectin-3 Overexpression in Well Differentiated Thyroid Carcinomas
BACKGROUND: Galectin-3 (Gal-3) is an anti-apoptotic molecule involved in thyroid cells transformation. It is specifically overexpressed in thyroid tumour cells and is currently used as a preoperative diagnostic marker of thyroid malignancy. Gal-3 expression is downregulated by wt-p53 at the transcri...
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Main Authors: | , , , , , , , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Public Library of Science
2011
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117790/ https://ncbi.nlm.nih.gov/pubmed/21698151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020665 |
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