Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level

TNF-related apoptosis-inducing ligand or Apo2L (Apo2L/TRAIL) is a promising anti-cancer drug owing to its ability to trigger apoptosis by binding to TRAIL-R1 or TRAIL-R2, two membrane-bound receptors that are often expressed by tumor cells. TRAIL can also bind non-functional receptors such as TRAIL-...

Fuld beskrivelse

Na minha lista:

Bibliografiske detaljer
Main Authors:	Morizot, A, Mérino, D, Lalaoui, N, Jacquemin, G, Granci, V, Iessi, E, Lanneau, D, Bouyer, F, Solary, E, Chauffert, B, Saas, P, Garrido, C, Micheau, O
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2011
Fag:	Original Paper
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3117243/ https://ncbi.nlm.nih.gov/pubmed/21072058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.144
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level

Lignende værker