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Give me a break, but not in mitosis: The mitotic DNA damage response marks DNA double strand breaks with early signaling events
DNA double-strand breaks (DSBs) are extremely cytotoxic lesions with a single unrepaired DSB being sufficient to induce cell death. A complex signaling cascade, termed the DNA damage response (DDR), is in place to deal with such DNA lesions and maintain genome stability. Recent work by us and others...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117133/ https://ncbi.nlm.nih.gov/pubmed/21412056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.8.15334 |
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