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Control of population stratification by correlation-selected principal components
In genome-wide association studies, population stratification is recognized as producing inflated type I error due to the inflation of test statistics. Principal component-based methods applied to genotypes provide information about population structure, and have been widely used to control for stra...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117098/ https://ncbi.nlm.nih.gov/pubmed/21133882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2010.01520.x |
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