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Principal-Component Analysis for Assessment of Population Stratification in Mitochondrial Medical Genetics

Although inherited mitochondrial genetic variation can cause human disease, no validated methods exist for control of confounding due to mitochondrial population stratification (PS). We sought to identify a reliable method for PS assessment in mitochondrial medical genetics. We analyzed mitochondria...

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Detalhes bibliográficos
Main Authors: Biffi, Alessandro, Anderson, Christopher D., Nalls, Michael A., Rahman, Rosanna, Sonni, Akshata, Cortellini, Lynelle, Rost, Natalia S., Matarin, Mar, Hernandez, Dena G., Plourde, Anna, de Bakker, Paul I.W., Ross, Owen A., Greenberg, Steven M., Furie, Karen L., Meschia, James F., Singleton, Andrew B., Saxena, Richa, Rosand, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032075/
https://ncbi.nlm.nih.gov/pubmed/20537299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.05.005
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