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Principal-Component Analysis for Assessment of Population Stratification in Mitochondrial Medical Genetics

Although inherited mitochondrial genetic variation can cause human disease, no validated methods exist for control of confounding due to mitochondrial population stratification (PS). We sought to identify a reliable method for PS assessment in mitochondrial medical genetics. We analyzed mitochondria...

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Bibliografische gegevens
Hoofdauteurs: Biffi, Alessandro, Anderson, Christopher D., Nalls, Michael A., Rahman, Rosanna, Sonni, Akshata, Cortellini, Lynelle, Rost, Natalia S., Matarin, Mar, Hernandez, Dena G., Plourde, Anna, de Bakker, Paul I.W., Ross, Owen A., Greenberg, Steven M., Furie, Karen L., Meschia, James F., Singleton, Andrew B., Saxena, Richa, Rosand, Jonathan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032075/
https://ncbi.nlm.nih.gov/pubmed/20537299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.05.005
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