Principal-Component Analysis for Assessment of Population Stratification in Mitochondrial Medical Genetics

Although inherited mitochondrial genetic variation can cause human disease, no validated methods exist for control of confounding due to mitochondrial population stratification (PS). We sought to identify a reliable method for PS assessment in mitochondrial medical genetics. We analyzed mitochondria...

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Main Authors: Biffi, Alessandro, Anderson, Christopher D., Nalls, Michael A., Rahman, Rosanna, Sonni, Akshata, Cortellini, Lynelle, Rost, Natalia S., Matarin, Mar, Hernandez, Dena G., Plourde, Anna, de Bakker, Paul I.W., Ross, Owen A., Greenberg, Steven M., Furie, Karen L., Meschia, James F., Singleton, Andrew B., Saxena, Richa, Rosand, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032075/
https://ncbi.nlm.nih.gov/pubmed/20537299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.05.005
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