Echinomycin and distamycin induce rotation of nucleosome core DNA.
When nucleosome cores reconstituted from chicken erythrocyte histones and a 160 bp DNA molecule are exposed to echinomycin, a bis-intercalating antitumour antibiotic, the DNA appears to rotate with respect to the histone octamer by about half a turn. New bands appear in patterns of DNAase I digestio...
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| Publicado en: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1986
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3763391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.17.6785 |
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