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The antiandrogenic effect of finasteride against a mutant androgen receptor
Finasteride is known to inhibit Type 2 5α-reductase and thus block the conversion of testosterone to dihydrotestosterone (DHT). The structural similarity of finasteride to DHT raises the possibility that finasteride may also interfere with the function of the androgen receptor (AR). Experiments were...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116931/ https://ncbi.nlm.nih.gov/pubmed/21386657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.10.15187 |
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