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Androgen Receptor-mTOR Crosstalk is Regulated by Testosterone Availability: Implication for Prostate Cancer Cell Survival

BACKGROUND: Signaling between androgen receptor (AR) and mTOR may be crucial for prostate cancer cells to endure the low androgen and suboptimal nutrient conditions produced by androgen deprivation therapy. MATERIALS AND METHODS: AR and mTOR cross-talk was examined in LNCaP cells exposed to either h...

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Detalhes bibliográficos
Publicado no:Anticancer Res
Main Authors: WU, YUE, CHHIPA, RISHI RAJ, CHENG, JINRONG, ZHANG, HAITAO, MOHLER, JAMES L., CLEMENT, IP
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355915/
https://ncbi.nlm.nih.gov/pubmed/21036700
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