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AMPK-mediated autophagy is a survival mechanism in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia

The present study was designed to investigate (i) the role of AMPK activation in inducing autophagy in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia, and (ii) whether autophagy offers a survival advantage under these harsh conditions. Low androgen and low oxy...

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Detalhes bibliográficos
Main Authors: Chhipa, Rishi Raj, Wu, Yue, Ip, Clement
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115439/
https://ncbi.nlm.nih.gov/pubmed/21554950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.04.008
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