Cargando...

C4-methyldeoxythymidine replacing deoxythymidine in poly[d(A-T)] renders the polymer resistant to the 3'----5' exonuclease activity of the Klenow and T4 DNA polymerases.

We previously reported that O4-alkyl dTTPs could replace, for short times, dTTP in polymer synthesis [Singer et al., PNAS 83, 26-32, 1986]. The reasons for such early termination of synthesis could be either proofreading or the eventual formation of weakly paired primer termini. Utilizing the known...

Descrición completa

Gardado en:
Detalles Bibliográficos
Autor Principal: Singer, B
Formato: Artigo
Idioma:Inglês
Publicado: 1986
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC311677/
https://ncbi.nlm.nih.gov/pubmed/3529040
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!