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Application of new catalytic phosphate protecting groups for the highly efficient phosphotriester oligonucleotide synthesis.

An effective procedure for the synthesis of oligonucleotides by the phosphotriester method has been developed. The procedure is based on the use of phosphate protecting groups enabling O-nucleophilic intramolecular catalysis in the reaction of internucleotide bond formation under the action of aryls...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Efimov, V A, Buryakova, A A, Dubey, I Y, Polushin, N N, Chakhmakhcheva, O G, Ovchinnikov YuA
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 1986
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3748819/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.16.6525
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