Application of new catalytic phosphate protecting groups for the highly efficient phosphotriester oligonucleotide synthesis.
An effective procedure for the synthesis of oligonucleotides by the phosphotriester method has been developed. The procedure is based on the use of phosphate protecting groups enabling O-nucleophilic intramolecular catalysis in the reaction of internucleotide bond formation under the action of aryls...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1986
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC311661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3748819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/14.16.6525 |
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