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Perturbation of cytoskeleton dynamics by the opposing effects of Rac1 and Rac1b

Rac1, a ubiquitously expressed member of the Rho GTPase family, plays a pivotal role in the regulation of multiple cellular processes including cytoskeleton reorganization, cell growth, differentiation and motility. Here we show that the tumor-specific splice variant of Rac1, Rac1b, negatively regul...

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Detalhes bibliográficos
Main Authors: Nimnual, Anjaruwee S, Taylor, Laura J, Nyako, Marian, Jeng, Hao-Hsuan, Bar-Sagi, Dafna
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116599/
https://ncbi.nlm.nih.gov/pubmed/21686260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.1.2.14427
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