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Itk: The Rheostat of the T Cell Response

The nonreceptor tyrosine kinase Itk plays a key role in TCR-initiated signaling that directly and significantly affects the regulation of PLCγ1 and the consequent mobilization of Ca(2+). Itk also participates in the regulation of cytoskeletal reorganization as well as cellular adhesion, which is nec...

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Autors principals: Grasis, Juris A., Tsoukas, Constantine D.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116522/
https://ncbi.nlm.nih.gov/pubmed/21747996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/297868
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