Itk Controls the Spatiotemporal Organization of T Cell Activation

During T cell activation by antigen-presenting cells (APCs), the diverse spatiotemporal organization of components of T cell signaling pathways modulates the efficiency of activation. Here, we found that loss of the tyrosine kinase interleukin-2 (IL-2)–inducible T cell kinase (Itk) in mice altered t...

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Détails bibliographiques
Auteurs principaux: Singleton, Kentner L., Gosh, Monica, Dandekar, Radhika D., Au-Yeung, Byron B., Ksionda, Olga, Tybulewicz, Victor L. J., Altman, Amnon, Fowell, Deborah J., Wülfing, Christoph
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248797/
https://ncbi.nlm.nih.gov/pubmed/21971040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001821
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