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Itk Controls the Spatiotemporal Organization of T Cell Activation
During T cell activation by antigen-presenting cells (APCs), the diverse spatiotemporal organization of components of T cell signaling pathways modulates the efficiency of activation. Here, we found that loss of the tyrosine kinase interleukin-2 (IL-2)–inducible T cell kinase (Itk) in mice altered t...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248797/ https://ncbi.nlm.nih.gov/pubmed/21971040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001821 |
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