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A biophysical protein folding model accounts for most mutational fitness effects in viruses
Fitness effects of mutations fall on a continuum ranging from lethal to deleterious to beneficial. The distribution of fitness effects (DFE) among random mutations is an essential component of every evolutionary model and a mathematical portrait of robustness. Recent experiments on five viral specie...
Wedi'i Gadw mewn:
| Prif Awduron: | , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116435/ https://ncbi.nlm.nih.gov/pubmed/21610162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017572108 |
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