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System-level feedbacks make the anaphase switch irreversible
The mitotic checkpoint prevents a eukaryotic cell from commencing to separate its replicated genome into two daughter cells (anaphase) until all of its chromosomes are properly aligned on the metaphase plate, with the two copies of each chromosome attached to opposite poles of the mitotic spindle. T...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116408/ https://ncbi.nlm.nih.gov/pubmed/21617094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102106108 |
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