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System-level feedbacks make the anaphase switch irreversible

The mitotic checkpoint prevents a eukaryotic cell from commencing to separate its replicated genome into two daughter cells (anaphase) until all of its chromosomes are properly aligned on the metaphase plate, with the two copies of each chromosome attached to opposite poles of the mitotic spindle. T...

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Bibliografske podrobnosti
Main Authors: He, Enuo, Kapuy, Orsolya, Oliveira, Raquel A., Uhlmann, Frank, Tyson, John J., Novák, Béla
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116408/
https://ncbi.nlm.nih.gov/pubmed/21617094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102106108
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