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Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation

The molecular mechanisms regulating noncanonical protein transport across cellular membranes are poorly understood. Cross-presentation of exogenous antigens on MHC I molecules by dendritic cells (DCs) generally requires antigen translocation from the endosomal compartment into the cytosol for protea...

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Detalles Bibliográficos
Main Authors: Zehner, Matthias, Chasan, Achmet Imam, Schuette, Verena, Embgenbroich, Maria, Quast, Thomas, Kolanus, Waldemar, Burgdorf, Sven
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116392/
https://ncbi.nlm.nih.gov/pubmed/21628571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102397108
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