N-glycosylation converts non-glycoproteins into mannose receptor ligands and reveals antigen-specific T cell responses in vivo

N-glycosylation is generally accepted to enhance the immunogenicity of antigens because of two main reasons. First, the attachment of glycans enables recognition by endocytic receptors like the mannose receptor (MR) and hence increased uptake by dendritic cells (DCs). Second, foreign glycans are pos...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Kreer, Christoph, Kuepper, Janina M, Zehner, Matthias, Quast, Thomas, Kolanus, Waldemar, Schumak, Beatrix, Burgdorf, Sven
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351675/
https://ncbi.nlm.nih.gov/pubmed/28036287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14314
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