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Tumour suppressor function of protein tyrosine phosphatase receptor-T

It is long thought that PTPs (protein tyrosine phosphatases) normally function as tumour suppressors. Recent high-throughput mutational analysis identified loss-of-function mutations in six PTPs in human colon cancers, providing critical cancer genetics evidence that PTPs can act as tumour suppresso...

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Bibliografiske detaljer
Main Authors: SCOTT, Anthony, WANG, Zhenghe
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116232/
https://ncbi.nlm.nih.gov/pubmed/21517784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20100134
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