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Tumour suppressor function of protein tyrosine phosphatase receptor-T
It is long thought that PTPs (protein tyrosine phosphatases) normally function as tumour suppressors. Recent high-throughput mutational analysis identified loss-of-function mutations in six PTPs in human colon cancers, providing critical cancer genetics evidence that PTPs can act as tumour suppresso...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116232/ https://ncbi.nlm.nih.gov/pubmed/21517784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20100134 |
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