Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T

Protein tyrosine phosphatase receptor-type T (PTPRT) is the most frequently mutated tyrosine phosphatase in human cancers. However, the cell signaling pathways regulated by PTPRT largely remain to be elucidated. Here, we show that paxillin is a direct substrate of PTPRT and that PTPRT specifically r...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhao, Yiqing, Zhang, Xiaodong, Guda, Kishore, Lawrence, Earl, Sun, Qun, Watanabe, Toshio, Iwakura, Yoichiro, Asano, Masahide, Wei, Lanlan, Yang, Zhirong, Zheng, Weiping, Dawson, Dawn, Willis, Joseph, Markowitz, Sanford D., Satake, Masanobu, Wang, Zhenghe
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823898/
https://ncbi.nlm.nih.gov/pubmed/20133777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914884107
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