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Etoposide induces heritable chromosomal aberrations and aneuploidy during male meiosis in the mouse
Etoposide, a topoisomerase II inhibitor widely used in cancer therapy, is suspected of inducing secondary tumors and affecting the genetic constitution of germ cells. A better understanding of the potential heritable risk of etoposide is needed to provide sound genetic counseling to cancer patients...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31160/ https://ncbi.nlm.nih.gov/pubmed/11274416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061404598 |
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